Dr. Nasna Nassir is an Assistant Professor in Human Genetics at the Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai Health, and Center for Applied and Translational Genomics. Her research lies at the interface of human genomics and translational neuroscience, focusing on how genetic variation shapes neurodevelopmental disorders, neurodegeneration, and brain tumors. She combines population-scale genomics with functional biology to bridge the gap between DNA sequence variation and disease mechanisms.
Dr. Nassir received her doctoral training in Biological Sciences from the Indian Institute of Technology Madras and completed postdoctoral training in human genetics at MBRU. She has further strengthened her translational perspective through a professional certification in Artificial Intelligence in Healthcare from MIT Sloan School of Management. Her work integrates whole-genome sequencing and pangenome graphs to improve variant interpretation in Middle Eastern and South Asian populations, contributing to regional genome initiatives and precision medicine efforts.
Dr. Nassir’s group employs CRISPR/Cas9 genome editing, stem cell-derived neuronal models, brain organoids, and single-cell transcriptomics to functionally validate disease-associated variants and advance allele-specific therapeutic strategies such as antisense oligonucleotides. More recently, her research has expanded into glioblastoma, where she combines spatial multi-omics and machine learning to identify early biomarkers, stratify disease subtypes, and discover therapeutic targets. Since joining MBRU, Dr. Nassir is engaged in teaching, supervising students and fostering national and international collaborations. She is deeply committed to mentoring the next generation of scientists and advancing genomics and precision medicine in the region.
Academic Appointments
Assistant Professor - Human Genetics
Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), United Arab Emirates
Scientist
Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), United Arab Emirates
Postdoctoral Research Fellow
Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), United Arab Emirates
Senior Research Fellow
Indian Institute of Technology Madras, India
Research Exchange Program (Japan Society for the Promotion of Science)
Osaka University, Japan
Professional Education
Artificial Intelligence in Healthcare
MIT Sloan School of Management, United States
Doctor of Philosophy in Biological Sciences
Indian Institute of Technology Madras, India
Master of Science (Research) in Biological Sciences
Indian Institute of Technology Madras, India
Bachelor of Technology in Biotechnology
National Institute of Technology Calicut, India
Teaching
- Techniques in Biomedical Sciences
- Systems Biology
- Molecular Genomics
- Genomics
- Bioinformatics
Honors and Awards
Internal Research Grant (Principal Investigator)
Mohammed Bin Rashid University of Medicine and Health Sciences
Best Research Paper Award, Second Forum for Women in Research
University of Sharjah
Best Poster Award
9th Pan Arab Human Genetics Conference
Postdoctoral Fellowship Award
Al Jalila Foundation, Dubai, UAE
Life Sciences Switzerland Travel Award
University of Geneva, Switzerland
Junior/Senior Research Fellowship (HTRA category)
Ministry of Human Resource Development, Government of India
Research Talent Search Program Grant (USD 30,000 student project)
Government of India
Publications
Membership of Professional Bodies/Associations
- Associate Member, Human Pangenome Reference Consortium (HPRC)
- Member, Sigma Xi – The Scientific Research Honor Society, Stanford University, USA
- Invited Expert Assessor (Genomics), UKRI Metascience Novelty Indicators Challenge, University of Sussex & RAND Europe, 2026
- Member, Human Cell Atlas (Middle East)
Research Interests
- Human genomics and variant interpretation using whole-genome sequencing to elucidate the genetic basis of neurogenetic disease.
- Development and application of pangenome references and population genomics for underrepresented Middle Eastern and South Asian populations.
- Genetic architecture of neurogenetic disorders and functional validation of disease-associated variants.
- Design and evaluation of gene-based therapeutic modalities, including allele-specific antisense oligonucleotides.
- CRISPR/Cas9-based functional genomics in stem cell–derived neuronal models and brain organoids.
- Single-cell, spatial transcriptomics, and multi-omics integration to resolve cellular states and disease mechanisms.
- Biomarker discovery and patient stratification in glioblastoma and precision neuro-oncology.
- Integration of machine learning and artificial intelligence with genomics to model disease trajectories and enable precision medicine.
Clinical And Community Service
- Hosted and coordinated numerous laboratory observerships for high-school and undergraduate students, providing early exposure to genomics and biomedical research.
- Contributes to capacity-building initiatives at MBRU by supporting training programs and hands-on learning experiences in genomics and translational research.